Tylosin Tartrate for Injection
Tylosin Tartrate for Injection
Active Ingredients
Each vial contains: Tylosin (as tylosin tartrate) 2 g
Pharmacodynamic
Tylosin tartrate is a macrolide antibiotic that is active mostly against Mycoplasmas, and also against Gram-positive bacteria and some Gram-negative bacteria. The sensitive bacteria have Staphylococcus aureus, Streptococcus pyogens, Streptococcus pneumoniae, Corynebacterium pyogenes.
Pharmcokinetic
After intramuscular administration tylosin is quickly absorbed. It is widely distributed to the organs and tissues of animals, the organs concentration after injection is higher than 2-3 times of that after oral administration. But it is not easy to penetrate into cerebrospinal fluid. The apparent volume of distribution for dogs and cattle are 1.7 L//kg and 1.1 L/kg, respectively. Tylosin concentration in milk is 20% of serum concentration. Unmetabolised tylosin is excreted in the urine and bile. The half-life of tylosin is 0.9 h in dogs and 0.95-2.3 h in calves, respectively.
Indications
Swine and poultry
For treatment of infections caused by Mycoplasmas and Gram-positive bacteria sensible to tylosin.
Dosage & Administration
Calculated on tylosin. Subcutaneous or intramuscular injection: swine and poultry: at the dosage of 5-13 mg/kg BW as a single injection.
Cautions
* Not for human use.
* Keep out of reach of children.
* May cause local irritation.
* Persons with a known hypersensitivity to tylosin should avoid exposure to this product.
Withdrawal Time
Animal Species |
Products |
Withdrawal time |
Swine |
Meat and offal |
21 days |
Poultry |
Meat and offal |
28 days |
Packing Size
Vials of 2 g
Storage Conditions
Store in an airtight container and in a dry place.
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